GHK-Cu Peptide Drops

GHK-Cu Liquid Drops Product Information

DISCLAIMER: By purchasing from Triumphant Labs you agree that you are purchasing Research Chemicals which are in no way intended for use in humans.

GHK-Cu, or Glycyl-Histidyl-Lysine-Copper, is a remarkable peptide naturally found in human blood plasma, urine, and saliva. Discovered in the early 1970s, it has captured the interest of researchers for its promising benefits in health and skincare. 

In terms of its structure, GHK-Cu comprises three amino acids—glycine, histidine, and lysine—linked to a copper ion. It forms stable complexes with copper at physiological pH levels, which enables the safe transport of copper into cells, thus influencing gene expression and various cellular functions. 

GHK-Cu's regenerative properties are linked to its unique interaction with copper—a crucial element for many organisms. Copper transitions between oxidized Cu(II) and reduced Cu(I) states, acting as an important co-factor in cellular processes like respiration, antioxidant defenses, and connective tissue synthesis [R]. 

Research indicates that GHK-Cu can alter gene expression, impacting about 31.2% of genes in these studies. This includes both increases and decreases in gene activity, contributing to its diverse protective and healing effects. Notably, GHK-Cu encourages the creation of collagen and elastin, which are crucial for skin structure and elasticity [R]. 

In terms of its antioxidant capabilities, GHK-Cu neutralizes harmful lipid peroxidation by-products linked to conditions like diabetes and neurodegenerative disorders. Its anti-inflammatory effects reduce levels of pro-inflammatory cytokines such as TNF-α and IL-6, and lower NF-κB activity, a complex that regulates DNA transcription and cell survival [R]. 

Another significant benefit of GHK-Cu is its role in wound healing. It boosts the production of growth factors, including VEGF and FGF-2, essential for angiogenesis—the process of new blood vessel formation. This is crucial for delivering nutrients and oxygen to repair tissues [R]. 

When it comes to skincare, GHK-Cu is a popular ingredient in anti-aging products for its ability to firm skin, diminish wrinkles, and enhance elasticity. It helps to tighten sagging skin, repairs barrier proteins, and fosters wound healing. Additionally, GHK-Cu shields skin against UV damage and can enhance overall skin appearance [R].

Common Questions

Does GHK-Cu activate stem cells?

GHK-Cu has been shown to affect stem cell behavior significantly. Research indicates that while low copper levels are crucial for stem cell proliferation, GHK-Cu, with its higher copper content, encourages stem cells to move towards differentiation. This suggests that GHK-Cu supports the process of differentiation, rather than activating or initiating the proliferation of stem cells. For further reading, check out this study.

Does copper peptide help with hair growth?

Indeed, copper peptides like GHK-Cu are beneficial for hair growth. Research demonstrates that GHK-Cu promotes hair growth by enhancing the production of vascular endothelial growth factor and reducing the generation of transforming growth factor beta. Furthermore, it encourages the proliferation of dermal papilla cells, which are crucial for hair follicle health. These functions help keep hair follicles from prematurely entering the regressive phase, while bolstering the growth phase and minimizing cell death (apoptosis) within these follicles. For more information, check out the studies here and here.

What Copper Peptide GHK-Cu Benefits Have Been Studied?

Several potential benefits and applications of the copper-binding peptide GHK-Cu have been studied.

• Skin delivery and cosmetic applications: Liposomes have been investigated as carriers for GHK-Cu to deliver the peptide to the skin. GHK-Cu-loaded liposomes demonstrated inhibition of elastase activity, potentially reducing elastin degeneration and supporting skin structural integrity [R].

• Skin remodeling and anti-aging: GHK-Cu has been shown to increase production of key skin proteins like collagen and modulate the skin remodeling process by stimulating both breakdown and synthesis of dermal matrix components, exhibiting anti-aging and tissue renewing properties [R].

• Wound healing: Stimuli-responsive polymers based on polyaspartic acid, 2-acrylamido-2-methylpropane sulfonic acid, and sodium alginate were developed for controlled release of GHK-Cu. In vivo studies showed promising results for wound closure and healing [R].

• Anti-inflammatory and protective effects in acute lung injury: GHK-Cu treatment reduced reactive oxygen species production, increased superoxide dismutase activity, and decreased pro-inflammatory cytokines in lipopolysaccharide-induced acute lung injury models, suggesting a potential therapeutic approach [R].

• Antioxidant and antiglycant properties for neurodegenerative disorders: A new biotin-GHK conjugate (BioGHK) was synthesized and studied for its antioxidant, antiglycant, and antiaggregant properties, suggesting potential applications in treating or preventing biochemical reactions associated with neurodegenerative disorders [R].

For our most recent COA and third party lab test results for our GHK-Cu see our facts & questions page here.

See our blog for:

• Peptide Safety & Side Effects
• Peptide Handling & Proper Storage
• Peptide Dosing for Research Purposes

Legal Disclaimer: This product is sold as a pure compound for research purposes only and is not meant for use as a dietary supplement. Please refer to our terms and conditions prior to purchase.

Safety Information: Keep this product out of the reach of children. This material has limited research available about it and may result in adverse effects if improperly handled or consumed. This product is not a dietary supplement, but a pure substance, sold as a raw material. We attest exclusively to the quality, purity and description of the materials we provide. This product is for use and handling only by persons with the knowledge and equipment to safely handle this material. You agree to indemnify us for any adverse effects that may arise from improper handling and/or consumption of this product.

The articles and information on products that may be found on this website are provided exclusively for the purposes of providing information and education. These items are not pharmaceuticals or medications, and the Food and Drug Administration has not given permission for the treatment or prevention of any disease, medical condition, or ailment using them.